ionBooster

The ionBooster enhances sensitivity and lowers detection limits by increasing ionization efficiency in a wide range of applications.

The sensitivity of the system is extremely important in most MS analytical tasks. Compared to standard electrospray, the ionBooster offers a 5–100x gain in sensitivity for many compounds of interest in the fields of environmental analysis, food testing and therapeutic drug monitoring.

The ionBooster can be used with the latest Bruker amaZon speed, maXis, maXis impact or solariX MS systems, and is quickly and easily installed.

For a wide range of compounds, the ionBooster achieves sensitivities that rival those of industry-leading QQQs, while still providing the known benefits of MSn or accurate mass values with TIP™ (True Isotopic Pattern). The ionBooster has simple operating parameters and nitrogen consumption requirements that are similar to those of conventional sources.

Target Applications

ionBooster in Forensics

Ethyl-Glucuronids (EtG and EtS) are markers for alcohol misuse. The ionBooster source yields a sensitivity improvement of factor 10 for EtG, compared to a standard ESI source.

ionBooster in Food Safety

Extremely sensitive analytical methods are required for accurate low-level identification and quantitation of zero-tolerance compounds in food. The broad-spectrum antibiotic Chloramphenicol (CAP) is such a compound. Determination of CAP is often performed by LC-MS/MS using MRM measurements on traditional triple-quadrupole instruments. Using the ionBooster, CAP can be determined in an LC-MS full scan method for lower limit quantification and confirmation on a maXis  UHR-TOF system, without compromising other analytical information.