Ask Target | Syringe Filters

Choose Target Filters to remove particular contaminants from samples prior to analysis. Our syringe filters are designed to be single-use for your convenience and for laboratory efficiency. We offer filters with various materials and housings, with different pore sizes and diameters to cover a wide range of applications. Target Filters are very competitively priced, offer improved quality and consistent analytical results, and can be efficiently used prior to sensitive techniques such as HPLC, GC, IC, ICP, and dissolution testing.

Target Filters are your everyday filters for fast and efficient filtering.

When choosing a syringe filter, three main factors dictate your selection:

  • Sample Volume
  • Pore and Particulate Size
  • Filter Membrane Compatibility

1. Sample Volume

The diameter of the syringe filter depends on the sample volume!

Larger diameter syringe filters (e.g., 25mm) purify larger sample sizes because of their wide membrane area, which offers increased filtration speed over the smaller diameter filters.

Target Filters 25mm syringe filters can be chosen for filter samples less than 100mL.

13mm syringe filters are a popular choice for most chromatography methods and are typically chosen when the sample volume is less than 10mL.

2. Pore and Particulate Size

Two porosities of membranes are available for Target filters, 0.45 microns, and 0.22 microns.

The 0.45μm pore size is recommended to guard columns and HPLC instrumentation against damaging particulates. The latest trend is to develop methods with lower limits of detection, which in turn leads to columns of smaller particle size and the tubing’s internal diameter getting smaller and smaller. This trend directs the chromatographers to filter their samples to remove even smaller detrimental particles; thus it is recommended to use 0.2μm pore size filters.

3. Filter Membrane

Target Analysis, planning for the future, always keeps in stock the most used membrane types to cover a wide range of applications. The main selection criteria for your syringe filter membrane are solvent compatibility and field of application .

Nylon membranes are used for general laboratory filtration of chromatography samples prior to injection. Nylon is solvent-resistant and is compatible with both aqueous and organic solvents. Nylon binds to protein and should not be used when protein recovery is meaningful. Nylon syringe filters have a yellow ring around the housing body for easy identification.

PTFE hydrophobic is chemically resistant to all solvents, acids, and bases. PTFE does not carry extractables to the filtrate. PTFE syringe filters have a red ring around the housing body for easy identification.

PVDF (polyvinylidene difluoride) is a solvent-resistant membrane and is recommended for chromatography sample filtration and general biological filtration. PVDF is a low-protein binding membrane and compatible with both aqueous and organic solvents. PVDF syringe filters have a purple ring around the housing body for easy identification.

RC (Regenerated Cellulose) is a very low-protein binding membrane and is ideal for aqueous-based samples. RC is compatible with organic solvents. RC membranes are an excellent choice when maximum protein recovery in filtrate is critical. RC syringe filters have a pink ring around the housing body for easy identification.


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