Simulated Moving Bed Chromatography (SMBC) Systems

SMB chromatography saves time and money in the lab

SMBC is increasingly applied as a separation technique in the pharmaceutical industry, production of fine chemicals, and in the field of bioengineering

SMB is a method in process chromatography that enables substance mixtures to be continuously separated and extracted in two fractions. Its efficiency is significantly higher than batch chromatography, through better utilization of the column stationary phase.  Although in principle limited to two fraction separations, each partial fraction can be separated into further fractions by repeated use of the SMB process – down to binary substance mixtures.

Typically, the SMB process is used for two-component mixtures, like chiral separations or mixtures with a “leading” or a “trailing” key product peak in the chromatogram.

Why buy SMB?

  • Work faster, save space – Get higher productivity and purity than with comparable batch systems – with an even smaller SMB system
  • Reduce your costs – Save up to 90% of the solvent and reduce the solid phase costs up to 80%
  • Keep your sample concentrated – Gain nearly undiluted product and minimize concentration efforts

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