CHRONECT Extract Collector | Alias™
Autosampler, Fraction Collector

Multipurpose sample handling device

1. as a fraction collector

ALIAS™ is a multipurpose sample handling device that has been installed in hundreds of labs and is known for its ease of use, flexibility, and rugged reliability.In the CHRONECT “Sytems,” the ALIAS is used as a fraction collector for applications requiring preservation of key analytes and/or products of upstream separations, under complete and integrated control of the CHRONOS software.

2. as an autosampler

ALIAS™ is a generic autosampler for HPLC and LC-MS using state-of-the-art injection technology with fast injection and wash cycles. Designed to fit any system for any application. Multi-solvent needle wash virtually eliminates carry-over. ALIAS™ handles well plates and sample vials, either open or sealed, and provides true 4°C sample cooling. Its compact, stackable design and unrivalled performance make the ALIAS™ autosampler the best fit for your (U)HPLC system.

ALIAS™ UHPLC | ALIAS™ is also available as a UHPLC compatible version permitting injection into UHPLC systems operated at pressures as high as 18,000 PSI. A special injection routine has been developed to eliminate influence of sample loop decompression on injection performance. The UHPLC version can also be equipped with sample cooling.

ALIAS™ Prep LC | A special modification for large volume injections turns the ALIAS™ into a perfect injector for your preparative LC system. The ALIAS™ Prep version holds 24 vials of 10 mL and uses a 2.5 mL syringe. Needles, tubing and sample loop have larger capacity and allow rapid injection of sample volumes up to 10 mL.

CHRONECT Extract Collector

Key Features

  • Compact, stackable design
  • Reliable performance
  • Collect into well plates or individual tubes (open or sealed)
  • Holds up to 24 vials of 10 mL each
  • Metal-free sampling with silica-coated steel needle and PEEK valve (option)
  • Reagent addition and mix capabilities for derivatization, dilution, internal standard addition
  • Integrated Stream Switching (ISS): optional extra high pressure 6-port switching valve for column switching or other stream switching applications up to 18,000 PSI
  • Quick-fit injection valve for fast service
  • Maintain temperature control on collected samples down to 4o C.
  • Efficient, multi-solvent needle wash (virtually eliminates carry-over)
  • Optional 6-port solvent selection valve (SVV) for extended selection of reagents for needle wash and reagent addition (option)


Injection modes Full-loop
Partial loop-fill
Pressure Assisted Sample Aspiration using ~10 PSI sample
headspace pressure to avoid air bubbles in sample lines.
Injection volume Programmable from 0 μl – 9999 μL
1 μL increments
Max injection volume depends on installed sample loop and injection mode
Injection precision Full-loop injection ‹ 0.3% RSD
Partial loop-fill ‹ 0.5% RSD
μL -pick-up ‹ 1.0% RSD
For injection volumes › 5 μL
Sample viscosity 0.1 – 5 cP  
Injections per vial/well Max 9  
Syringe volume 500 μL standard
250, 1000 and 2500 μL optional 
Needle wash
Inside and outside needle wash with drying. Wash can be programmed between injections and between vials/wells.
1 solvent
5 additional wash solvents
Programmable volume from a 250 μL wash reservoir
SSV option required
Injection cycle time ‹ 60 seconds ‹ 20 seconds, with typical 10 μL injection (loop fill with rinse buffer)
Valve switching time 60 msec  
Wetted parts SS316, PTFE, TEFZEL, VESPEL, glass, For Bio-kit option:
PEEK and coated-steel (needle) instead of SS316
Carry-over ‹ 0.05% with standard wash
Typically ‹ 0.01% with extra wash
“zero carry-over” can be accomplished with ALIAS™ wash capabilities
Sample capacity Microtiter plates: 2
Vials: 2x 48 (1.5 mL)
or 2x 12 (10 mL) – optional
Microtiter plates according to SBS standards. 96-well high and low and 384-well.
Maximum vial/MTP height 47 mm including cap
Sample cooling Factory installed option (Peltier technology) Minimum: 4°C ± 2°C
Maximum: ambient temp -3°C
Measured as air temperature in sample compartment for
maximum ambient temperature 25°C and maximum humidity 80% 




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