EVOQ LC – Triple Quad MS


The EVOQ triple quadrupole for liquid chromatography (LC-TQ) was designed for a singular purpose—to reliably quantify thousands of real samples in the fastest sample-to-report time possible. 

Today Bruker is pioneering the migration of technology from research to commercial laboratory. 

The EVOQ LC-TQ delivers MRM assays with exceptional sensitivity and accuracy

  • Easily obtain ultra-high sensitivity for small molecules and biomolecules as a result of the innovative interlaced quadrupole (IQ) dual ion funnel.
  • Confidently run matrix-rich samples on the robust orifice plate-based API interface.
  • Efficiently analyze thermally labile molecules at high flow rates with the vacuum insulated probe (VIP) heated electrospray probe.
  • Save time using exception-based data-review software that makes it easier to highlight chromatograms that do not meet preset method criteria.

Accuracy and Precision
The EVOQ LC-TQ routinely achieves an unbeatable limit of quantitation (LOQ) in matrix.

EVOQ LC – Triple Quad MS

Key Features

  • Workflow design – Simple, intuitive, powerful
    The powerful software suite for the EVOQ LC-TQ series simplifies workflows from sample to report, with instrument and user interfaces that adapt to your needs.
  • Client-server-based software – integrating instruments for high throughput and ease of use
    The software integrates acquisition and data handling together, and allows the installation to be tailored specifically to the laboratory’s needs. Whether this is one instrument at one station or a centralized server with several mass spectrometers feeding data in from all over the world, the Bruker network maximizes system uptime.
  • Libraries – User-created or commercial library support
    The EVOQ GC-TQ gives users the freedom to create an unlimited number of libraries to share with partners around the world, which can be shared between different clients from one or more servers. The use of pre-determined libraries and databases commercially available in NIST format represents a substantial time-saving.
  • MRM Method Builder – Designed by chromatographers
    The EVOQ LC-TQ’s autofill function removes the need to know the MRM transition of an analyte. A simple drag-and-drop of the compound from the factory-installed compound library, which contains more than 3000 MRM transitions, lets the software set up the method and manage the TQ duty cycle.


  Qube  Elite Elite ER
mass range  10 – 1,250  10 – 1,250  10 – 2,000
size [mm]  530 x 450 x 700  530 x 450 x 700 530 x 450 x 700



Game changer for routine multiple reaction monitoring (MRM) assays

Accuracy & precision

Record-breaking full sensitivity resolution (FSR) of > 80,000.


Five orders of magnitude dynamic range achieved at UHPLC speeds due to 50 GBit/sec sampling technology-definitive trace analysis from complex, high-background matrices.


One-shot acquisition with triple-quadrupole sensitivity ensuring qualitative and quantitative
results in one LC run with fastest time-to-success.

Key applications

Food Analysis and Testing

Ideal for testing for pesticide and veterinary drug residues, and other contaminants in food products. The high MRM speed allows high throughput chromatography testing, delivering a wide scope of applications and unprecedented flexibility.

Environmental Analysis

The MRM software databases allow the simple set up of methods to screen and quantify hundreds of compounds, even those detected in low amounts.

Forensic Toxicology

Body fluids are amongst the toughest matrices for analysis. The EVOQ GC-TQ series delivers sustained sensitivity and robustness to meet the unique challenges of forensic analysis, while minimizing maintenance downtime.

Targeted Metabolomics

The software suite brings the EVOQ GC-TQ system in line with Bruker’s well known instrumentation and software for Metabolomics and Phenomics investigations. Users can now integrate data from every Bruker instrument using the same workflows.

System Components

VIP-HESI dual source

VIP-HESI dual source

Next generation in Mass Spectrometry sensitivity
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