CHRONECT Mistral™| Temperature Controller

Stable and precise oven

Dependable temperature control for better separations

The CHRONECT Mistral Cool is a high-performance HPLC/UHPLC column temperature controller. Powered by Peltier technology combined with a forced air oven for rapid equilibration, the CHRONECT Mistral Cool can control temperatures accurately over a range of 5o C. to 75o C. This range is broad enough to accommodate virtually any chromatographic separation. The stability of the oven is further enhanced with the circulating air bath, while the mobile phase pre-heater reduces any temperature gradients across the column.

With its vapour sensor and integrated solvent pre-heater, the MISTRAL™ offers stable and precise temperature control to optimize your HPLC or UHPLC assay. As you will easily recognize, retention times will be more constant with constant temperature, but varying the temperature can also be of great help to tune selectivity, improve peak shape and reduce analysis time. Plus, high temperatures reduce column back pressure significantly, allowing higher solvent flow rates, narrower columns or smaller particles.


Key Features

  • 5°C – 75°C with multi-position column switching
  • Temperature gradient programming
  • Excellent temperature stability
  • Integrated solvent pre-heater
  • 5°C – 90°C
  • Vapor sensor for safety
  • Automated column selection. Select up to 6 different columns via the keyboard or the PC.
  • UHPLC valves available


Parameter Value Conditions
Temperature range  5°C – 90°C, with 1°C increments 5°C – 75°C, with 1°C increments, if optional Column Selection Valve is installed Ambient temperature and humidity influence the lower temperature limit of the MISTRAL™. Typically, a ΔT of 18°C is feasible.
Temperature accuracy  Better than 0.1°C Measured at 30°C in the centre of the oven compartment
Temperature stability  Better than 0.1°C Measured at 30°C in the centre of the oven compartment
Temperature reproducibility Better than 0.1°C In the centre of the oven compartment
Temperature gradient Better than 0.2°C Measured in the column area
Temperature change Up: 10°C/min from 40° to 60°C Down: 2°C/min from 60°C to 40°C
Time programmable temperature change Time base: 9hr59 total time with 1-minute increments Maximum 10 programmable steps
Programmable temperature ramp Up: 0.1 – 5.0°C/min Down: 0.1 – 1.5°C/min (75°C to 25°C) It is possible to program a ramp up to 9.9°C/min; however, only the ramp ranges specified can be guaranteed for the actual temperature ramp
Dimensions (H x W x D) 600 x 170 x 345 mm (h x w x d)






System Components

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