Highly sensitive refractive index detector for liquid chromatography

Analytical refractive index detector

The AZURA RID 2.1L is a sensitive and competitively priced differential refractometer. It is suitable for detecting compounds with little or no UV activity such as alcohols, sugars, lipids or polymers. This instrument is designed for use in analytical HPLC (high performance liquid chromatography) as well as under certain conditions for GPC (gel permeation chromatography) applications. The intelligently designed optical unit with advanced temperature control ensures high sensitivity, fast baseline stabilization, and excellent reproducibility. Furthermore, the long-life LED, highly pressure resistant flow cell, improved safety features and enhanced diagnostics functions guarantee easy handling and minimal maintenance. The wide linear dynamic range, its low internal volume of 43 µl from the inlet to the flow cell and 10 ml/min maximum flow rate make the AZURA RID 2.1L the perfect choice for most laboratory tasks. This detector can be controlled with OpenLAB® EZChrom, ClarityChrom®, Chromeleon® and PurityChrom® Bio software, as well as from the AZURA Mobile Control app (stand-alone operation), via LAN or through analog input/output, allowing it to be integrated into almost any LC system.


Detector typeRefractive index detector
Light sourceLong-life LED
Detection channels1
Refractive index range1.00 – 1.75 RIU
Noise± 2.5 nRIU
Drift200 nRIU/h
Linearity> 1000 µRIU
Flow cell5 bar back pressure resistance flow cell included
Max. flow rate10 ml/min (pure water)
Flow cell volume15 µl (43 µl dispersion volume)
Wetted materialsStainless steel / quartz / PTFE
Temperature controlOFF, 30 – 55 °C (1 °C increment)
Time constants0.00 / 0.01 / 0.02 / 0.05 / 0.1 / 0.2 / 0.5 / 1.0 / 2.0 / 5.0 / 10.0 s
Maximum data rate100 Hz (LAN)/20 Hz (Analog)
AutozeroFull range
Leak sensorYes (internal and external leak management)


Power supply100 – 240 V, 50 – 60 Hz, 65 W
Dimensions361 x 158 x 523 mm (W x H x D)
Weight10.8 kg
InputsError (IN), Start (IN), Autozero, Flush (IN)
OutputsEvent 1, Start (OUT), Error (OUT), + 5 V, 24 V Valve
Analog outputs1 x 0- 2.5 V scalable, 20 bit, offset adjustable
ControlMobile Control, software, event control, analog, terminal protocol
Interfaces2 x LAN (RJ-45, dual IP-stack), USB (service only), multi-pin connector, analog (cinch connector)
GLPDetailed report including operating hours, light source operating hours
DisplayMobile Control (optional)
Ambient conditionsTemperature range: 4 – 40 °C, 39.2 – 104 °F, Humidity: below 90 % noncondensing
Highly sensitive refractive index detector for liquid chromatography
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