CHRONECT Multiplexing

Modern samplers for automation and complex sample preparation

With the CHRONECT Workstation Multiplexing a solution for better utilization of LC-MS systems was developed. It allows up to four LC columns and pumps to be installed in parallel. By intelligent valve switching, only the target analytes are transferred to the mass spectrometer. The rest of the matrix does not load the mass spectrometer.

There is also no loss of time for reconditioning, since the next measurement can already be started with another column. By using up to four HPLC channels in parallel, the desired sections of four samples can be transferred to the LC-MS in a time-interleaved manner and analyzed in close succession. Thus, the sample throughput of LC-MS systems can be increased up to fourfold.

CHRONOS organizes the connection to the LC-MS.
All CHRONECT systems are able to process multiple batches/assays quickly and reliably with maximum analytical performance without supervision.

CHRONECT Multiplexing

Key Features

The target analytes in liquid chromatography often elute in a very small time slot. The matrix-related substances that elute later are of no interest to the analyst, but put a strain on the mass spectrometer. Normally this has to be awaited, as well as the reconditioning of the column.

  • A modified design of the sample trays enables very large sample capacities to be achieved.
  • Fast Injection is a particularly fast type of GC injection and enables particularly low-discrimination injections.
  • Smallest sample volumes can be handled better. The needle can be guided to the bottom of the vessel thanks to bottom sensing.
  • The Vortex Mixer allows automatic mixing and homogenization of samples.
  • A large selection of tools and modules allows optimal individual configurations.
  • The master software CHRONOS ensures optimal control and integration into existing chromatography systems and easy handling.

 CHRONECT
Multiplexing

The basis is a CHRONECT Robotic Autosampler and the HPLC pump SPH1299 from Spark. The entire control and intelligent time management is handled by the CHRONOS software platform. 

System Components

SPE Cartridges

SPE Cartridges

CHROspe SPE consumable, responsible for the efficient and reproducible extraction of analytes from samples, with maximum recoveries
Tool Change

Tool Change

Park Station and LC-MS Tool
Wash Module

Wash Module

Fast Wash Module and Solvent Module
Sample Storage

Sample Storage

The CHRONECT Symbiosis Sampler offers you various options for sample storage: from simple trays for three racks each with vials of different sizes to drawers that can be cooled as required.
Injection

Injection

Liquid injection by the PAL is characterized by a combination of precision, reproducibility and flexibility.
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